Maintaining Immunity after Immunization (U01 Clinical Trial Not Allowed)

The goal of this Funding Opportunity Announcement (FOA) is to promote research to improve our understanding of how vaccines against infectious agents lead to durable protective immunity. This initiative will support studies that define components and mechanisms of the immune system that determine such durability. Applications must propose the use of human cells/tissues to decipher the human response elicited through vaccination. Animal studies also may be included to elucidate mechanistic pathways not easily accomplished with human samples.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.