Improving Choice, Use, and Equitable Implementation of Biomedical HIV Prevention for Women (R01 Clinical Trial Optional)

This initiative will solicit research to target gaps in knowledge about barriers and facilitators to ring use, interventions to improve uptake, adherence, and persistence on the vaginal ring, and implementation science studies to improve access to and distribution of the ring. Research topics may include, but are not limited to: studies of individual, interpersonal, and structural factors that are barriers and facilitators to uptake of, adherence to, and persistence on the vaginal ring when the ring is delivered in real world settings (i.e., outside of clinical or open label extension trials); development and testing of behavioral interventions to encourage uptake, consistent use of, and persistence on the vaginal ring; and implementation science studies to understand implementation barriers and facilitators to delivery of the vaginal ring, and to optimize delivery of the ring.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.